Glomerulonephritis occurs when the glomeruli are damaged or inflamed. These structures filter waste, excess salts, and fluids from the blood to produce urine. Inflammation reduces their filtering ability, leading to waste buildup, fluid retention, and other complications. Acute glomerulonephritis usually appears suddenly, often after infections such as streptococcal throat or skin infections. Chronic glomerulonephritis develops gradually over months or years and may result from autoimmune diseases, long-standing hypertension, or other causes of sustained kidney injury.

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